Glycemic Control Of End Stage Renal Disease - 1277 Words

Glycemic Control in End-Stage Renal Disease The role of diabetes is highly significant in the development renal disease if not treated properly. The glycemic control is complicated in kidney failure patients due to complex challenges affecting glucose. The purpose of this paper is to identify how the phenomenon of interest impact relevant practice area, discuss two philosophical viewpoints influencing the chosen topic and incorporate patterns of knowing to the advanced practice role. Phenomenon of Interest The writer will examine the prevalence of diabetes among the patients with end-stage renal disease (ESRD), potential benefits, and harm during management of underlying cause, and analysis of glycemic index hemoglobin A1c (HgbA1c) in managing diabetic ESRD patients. Diabetes is one of the frequent reasons and common persistent complications of ESRD (Kovesdy, Park, Kalantar-Zadeh, 2010). According to the United States Renal Data System (USRDS), diabetes is the primary cause leading to ESRD. Among 20.8 million diabetic population, approximately 232,984 were affected by ESRD that accounted for increase in Medicare budget from 5.4% to 6.3% at the end of 2011 (United States Renal Data System [USRDS], 2013). Not everyone with diabetes develop ESRD, thus strictly controlling blood sugar level lower the chances of getting kidney disease (Mehrotra, Kalantar-Zadeh, Alder, 2011). Diabetic patient with ESRD need to understand pathophysiology and complications of poorShow MoreRelatedDiabetic Nephropathy Case Study1448 Words   |  6 Pagespresence of proteinuria is one of the major late microvascular complications of type 1 and type 2 diabetes mellitus and leading to a decline in renal function. In the present study, three important single nucleotide polymorphisms (SNPs) of the PPARG gene were analysed to understand the potential modifier effect of PPARG gene on the advancement of chronic kidney disease in DN. Methods: A total of 187 diabetic nephropathy patients (101 male and 86 female) with persistent urine albuminuria (300 mg/L) wereRead MoreDiabetic Microvascular : Leading Cause Blindness762 Words   |  4 PagesDiabetic microvascular complications are the leading cause of blindness, end-stage renal diseases, and other neuropathies due to hypoxia and ischemia in the retina, the kidney, and nerves. Thickening of the capillary basement membrane result in decreased tissue perfusion. Many people with type 2 diabetes present with microvascular complications because of the long duration of asymptomatic hyperglycemia that usually precedes diagnosis (Mccaine and Huther). Diabetic Retinopathy Diabetic retinopathyRead MoreThe Incidence And Severity Of Diabetic Nephropathy1269 Words   |  6 Pagesnephropathy. Obesity — A high body mass index (BMI) in patients with diabetes has been associated with an increased risk of chronic kidney disease. In addition, diet and weight loss may reduce albuminuria and improve kidney function among patients with diabetes Smoking — Smoking includes evidence of increases in albuminuria and the risk of end-stage renal disease and of decreased survival once dialysis is begun. Oral contraceptives — An initial report suggested a link between oral contraceptive useRead MoreResearch Study On Kidney Disease1433 Words   |  6 PagesIntroduction This chapter will focus on research to explore the background of kidney disease, quality of care, health literacy, perception and knowledge of kidney disease, and survey design. The literature review on kidney disease will provide the definition of kidney disease and the various stages that compromises it. Definition of Kidney Disease â€Å"The National Kidney Foundation criteria for diagnosis of Chronic Kidney Disease (CKD) are as follows: kidney damage for 3 months or longer, as defined by structuralRead MoreA Brief Note On Diabetic Kidney Disease ( Dkd )1108 Words   |  5 PagesDiabetic Kidney Disease Diabetic kidney disease (DKD) is defined kidney disease attributed to diabetes (versus chronic kidney disease, which may be due to numerous etiologies including diabetes). ADA recommends screening for nephropathy 5 years after diagnosis for type 1 diabetes and at diagnosis for type 2 diabetes. Screening includes urine albumin excretion (albumin/gr creatinine). ADA no longer uses the terms â€Å"micro ( 30 ug/mg Cr) and macroalbuminuria ( ug/mg Cr)†, but defines albuminuriaRead MoreThe Effect Of Empagliflozin ( Jardiance ), An Inhibitor Of Sodium Glucose Cotransporter 2944 Words   |  4 Pagesinsulin results in the body becoming resistant to normal levels of insulin. When the body becomes resistant, in advanced stages, insulin secreted cells in the pancreas becomes damaged, and eventually requires exogenous insulin to maintain sufficient levels. First line treatment for diabetes mellitus is currently a combination of diet and lifestyle modifications as well as oral glycemic agents. Therapy usually starts with Metformin, but based on doctor preferences, individual patient parameters, as wellRead MoreInternational Conference On Harmonization Guidelines1612 Words   |  7 Pagesis not available in Canada and is needed to shipping from US under the Health Canada Regulations (Part C, Division 5). 1.1 Background Diabetes mellitus is a common diseases in the world and Canada is diabetes mellitus. Diabetes Mellitus has been starting to grow all over the world. It is anticipated that the incidence of this disease will be increased dramatically in the next decade. The main reasons of this event are obesity, increasing the population mean age and reducing physical activities especiallyRead MoreAnalysis Of Drug Metformin : A Disorder Of The Endocrine System1053 Words   |  5 Pagessignificant number of patients who were diagnosed with diabetes will suffer from an end-stage renal disease (Ciccone, 2016). According to Mishra, Swaroop and Kandpa (2016), complications of diabetes are seen gradually, especially if the glucose level is not controlled (p. 55). Also, Li, Zheng, Buruku and De Kimpe (2004), explains that people with diabetes has difficulty or not able to produce insulin that controls the blood glucose. There are 2 types of diabetes, Type 1 or the insulin dependent diabetesRead MoreLab Report On The Urinary Concentration Of Tnf-1417 Words   |  6 Pagesparticipant in sterilized urine containers and used to determine albumin in 24 h urine specimen. The urine levels of the biomarkers were normalized to the urinary creatinine concentration to control for variations in hydration status. Serum and urinary TNF-ÃŽ ±: serum levels were measured by an enzyme-linked immune absorbent assay (ELISA) using commercially available standard kits (Quantikine high-sensitivity human TNF-ÃŽ ± Research Diagnostic Systems, Europe Ltd, Abington, UK). The urinary concentrationRead MoreInternational Conference On Harmonization Guidelines1802 Words   |  8 Pagesneeded some shipping process from United State of America under the Health Canada Regulations (Part c, Division 5). 1.1 Background Diabetes Mellitus is a common disease in the world and Canada. The number of diabetic patients has been starting to increase in most of the world countries. It is anticipated that the incidence of this disease will be increased dramatically in the next decade. The main reasons of this event are: a) obesity, b) increasing the mean age of the world population and c) reducing